This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems?
Dieser Kurs ist Teil der Spezialisierung Spezialisierung Systems Biology and Biotechnology
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Systems Level Reasoning | Molecules to Pathways
Pathways to Networks | Physical Forces and Electrical Activity in Cell Biology
Mathematical Representations of Cell Biological Systems | Simulations of Cell Biological Systems
Experimental Technologies | Network Building and Analysis
Bewertungen
- 5 stars56,28 %
- 4 stars25,51 %
- 3 stars9 %
- 2 stars5,06 %
- 1 star4,12 %
Top-Bewertungen von INTRODUCTION TO SYSTEMS BIOLOGY
A fantastic introductory course. One should really treat this as an overview that needs to be followed by further study.
It's a challenging subject. Don't expect to walk away from the course with a complete grasp of systems biology. However, this course is a fantastic place to start.
Great foundational material and insights from Prof. Iyengar that supports the 'disruptive' trends underway at the intersection of Computational Biology and Medicine.
Coursera make it different...
I'm pretty lucky to find a systems biology course like this.
Über den Spezialisierung Systems Biology and Biotechnology

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