Okay. So we have the problem say should we look at the protein and then the behavior was changed, okay? And then there is another kind of experiment you can do okay in the fly is actually then if you express. So in that case actually, if you knock out the protein, the cell maybe not function properly. But if you activate specifically those neurons, use some other method to activate them, then you will see how examination, what behavior was changed. This is the experiment people did. This is wild type of fly. You put two flies and then the sequence of the mating behavior is quite clear, right, follow and sing a song and also of tracing and then mating. And for this experiment actually people use a strategy. So this one, TIPA, is a trip channel. This channel is a temperature sensitive channel. That means you just need to increase the temperature a little bit, and then this channel will open, will activate the cell. Okay, so in this case, you just need actually to use this fruitless scale for to drive the tRP A1 expression. And that means, actually, all those fruitless neuron, you will express triple a1 channel. Then you'll increase the temperature and then those neuron will be activated. Then you'll see exactly when you activate certain neuron, that a single fly, a male fly, then show up this corresponding behavior we can see. We told a female fly there. She just do the mating behavior. So this means it's actually those fruitless neuron, expressing neuron. Really important to control this mating behavior. Okay, so if it's true, that's quite interesting, right? So people did another experiment here. So let's take a look, first, actually this one, as we mentioned, the fruitless protein is not functional in the female, because of suppressing, right? It's only the male can express. You see this is the control fly, a male fly, a female. You make staining of the fruit protein, and you see in the male, you have the protein. But females don't have. Okay, so in this case, people did again another experiment. The knock out, actually, that fruitless gene, okay, in both male and the female, and only expressed the female fruitless gene back to the fly. That means the female will express right now a male version of the fruit protein. And male of course still expressed the same male version of the fruit protein, right? And the people found, actually, in this case that the male is fine, is back to normal, Y type. But the female quite interesting, you see [LAUGH]. This is a female fly, transgenic female fly. And this a normal female. You see, this female is doing the same behavior as a male. So, this result is quite stimulating, right? Tells you, maybe, yeah, the fruit protein really is important drive to control the behavior